Research at the Department of Biochemistry

The staff of the institute at the CCM of Charité – Universitätsmedizin Berlin are involved in the various special research areas (SFB) of the German Research Foundation (DFG), national and international collaborative projects as well as in the excellence cluster "Neurocure".

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Research areas of the Department of Biochemistry

  • Biochemistry and systems biology of cellular metabolism.
  • The pathophysiology of inflammation.
  • The enzyme-evolution of lipoxygenases and glutathionperoxidases.
  • Analysis of the protein degradation by the Ubiquitin-Proteasome-System (UPS) as part of the immune response against viral infections and the role of the UPS in the development of neurodegenerative diseases like Multiple Sklerose, Parkinson or Alzheimer.
  • Molecular and structural analysis of the Ubiquitin-Proteasome-System.
  • The development of mathematical models to the computer-assisted simulation of metabolic processes.
  • The pathogenesis of cardio-vascular diseases.
  • Adipositas and metabolic syndrome.
  • The analysis of the molecular structure of proteins.